2010 |2009 |2008 | 2007 | 2006 | 2005 | 2004 | 2003 | bookchapters

Kemter E, Ratkolb B, Bankir L, Schrewe A, Hans W, Landbrecht C, Klaften M, Ivandic BT, Fuchs H, Gailus-Durner V, Hrabé de Angelis M, Wolf E, Wanke R, Aigner B (2010): Mutation of the Na+-K+-2Cl- cotransporter NKCC2 in mice is associated with severe polyuria and a urea-selective concentrating defect without hpyerreninemia. Am J Physiol Renal (Epub ahead of print)

Morgan H, Beck T, Blake A, Gates H, Adams N, Debouzy G, Leblanc S, Lengger C, Maier H, Melvin D, Meziane H, Richardson D, Wells, S, White J, Wood J, EUMODIC Consortium, Hrabé de Angelis M, Brown SDM, Hancock JM, Mallon AM (2010): EuroPhenome: a repository for high-throughput mouse phenotyping data. Nucleic Acids Res 38, D577-D585

Rosemann M, Ivashkevich A, Favor J, Dalke C, Hölter SM, Becker L, Rácz I, Bolle I, Klempt M, Rathkolb B, Kalaydjiev S, Adler T, Aguilar A, Hans W, Horsch M, Rozman J, Calzada-Wack J, Kunder S, Naton B, Gailus-Durner V, Fuchs H, Schulz H, Beckers J, Busch DH, Burbach JP, Smidt MP, Quintanilla-Martinez L, Esposito I, Klopstock T, Klingenspor M, Ollert M, Wolf E, Wurst W, Zimmer A, Hrabé de Angelis M, Atkinson M, Heinzmann U, Graw J (2010): Microphthalmia, parkinsonism, and enhanced nociception in Pitx3 (416insG) mice. Mamm Genome 21, 13-27

Tocchetti A, Ekall Soppo CB, Zani F, Bianchi F, Gagliani MC, Pozzi B, Rozman J, Elvert R, Ehrhardt N, Rathkolb B, Moerth C, Horsch M, Fuchs H, Gailus-Durner V, Beckers J, Klingenspor M, Wolf E, Hrabé de Angelis M, Scanziani E, Tacchetti C, Scita G, Di Fiore PP, Offenhäuser N (2010): Loss of the Actin Remodeler Eps8 Causes Intestinal Defects and Improved Metabolic Status in Mice. PLoS One 5 (3), e9468

Enard W, Gehre S, Hammerschmidt K, Höler SM, Blass T, Somel M, Brückner MK, Schreiweis C, Winter C, Sohr R, Becker L, Wiebe V, Nickel B, Giger T, Müller U, Groszer M, Adler T, Aguilar A, Bolle I, Calzada-Wack J, Dalke C, Erhardt N, Favor J, Fuchs H, Gailus-Durner V, Hans W, Hölzlwimmer G, Javaheri A, Kalaydjiev S, Kallnik M, Kling E, Kunder S, Moßbrugger I, Naton B, Racz I, Rathkolb B, Rozman J, Schrewe A, Busch DH, Graw J, Ivandic B, Klingenspor M, Klopstock T, Oller M, Quintanilla-Martinez L, Schulz H., Wolf E, Wurst W, Zimmer A., Fisher SE, Morgenstern R, Arendt T, Hrab&eacut; de Angelis M, Fischer J, Schwarz J, Pääbo S (2009): A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice. Cell 137, 961-971

Fuchs H, Gailus-Durner V, Adler T, Pimentel JA, Becker L, Bolle I, Brielmeier M, Calzada-Wack J, Dalke C, Ehrhardt N, Fasnacht N, Ferwagner B, Frischmann U, Hans W, Hölter SM, Hölzlwimmer G, Horsch M, Javaheri A, Kallnik M, Kling E, Lengger C, Maier H, Mossbrugger I, Mörth C, Naton B, Nöth U, Pasche B, Prehn C, Przemeck G, Puk O, Racz I, Rathkolb B, Rozman J, Schäble K, Schreiner R, Schrewe A, Sina C, Steinkamp R, Thiele F, Willershäuser M, Zeh R, Adamski J, Busch DH, Beckers J, Behrendt H, Daniel H, Esposito I, Favor J, Graw J, Heldmaier G, Höfler H, Ivandic B, Katus H, Klingenspor M, Klopstock T, Lengeling A, Mempel M, Müller W, Neschen S, Ollert M, Quintanilla-Martinez L, Rosenstiel P, Schmidt J, Schreiber S, Schughart K, Schulz H, Wolf E, Wurst W, Zimmer A, Hrabé de Angelis M (2009): The German Mouse Clinic: A Platform for Systemic Phenotype Analysis of Mouse Models. Curr Pharm Biotechnol 10, 236-243

Gailus-Durner V, Fuchs H, Adler T, Aguilar Pimentel A, Becker L, Bolle I, Calzada-Wack J, Dalke C, Erhardt N, Ferwagner B, Hans W, Hölter SM, Hölzlwimmer G, Horsch M, Javaheri A, Kallnik M, Kling E, Lengger C, Mörth C,  Mossbrugger I, Naton B, Prehn C, Puk O, Rathkolb B, Rozman J, Schrewe A, Thiele F, Adamski J, Aigner B, Behrendt H, Busch DH, Favor J, Graw J, Heldmaier G, Ivandic B, Katus H, Klingenspor M, Kremmer E, Ollert M, Quintanilla-Martinez L, Schulz H, Wolf , Wurst W, Hrabé de Angelis M (2009): Systemic First-Line Phenotyping. In:  Gene Knockout Protocols: 2nd Ed., Kühn R, Wurst W (eds.) Methods Mol Biol 530, 463-510

Isensee J, Meoli L, Zazzu V, Nabzdyk C, Witt H, Soewarto D, Effertz K, Fuchs H, Gailus-Durner V, Busch D, Adler T, Hrabé de Angelis M, Irgnag M, Otto C, Noppinger PR (2009): Expression Pattern of Gpr30 in LacZ Repoerter Mice. Endocrinology 150, 1722-1730

Khasawneh J, Schulz MD, Walch A, Rozman J, Hrabé de Angelis M, Klingenspor M, Buck A, Schwaiger M, Saur D, Schmid RM, Klöppel G, Sipos B, Greten FR, Arkan MC (2009): Inflammation and mitochondrial fatty acid beta-oxidation linke obesity to early tumor promotion. Proc Natl Acad Sci USA 106, 3354-3359

Noyes HA, Alimohammadian MH, Agaba M, Brass A, Fuchs H, Gailus-Durner V, Hulme H, Iraqi F, Kemp S, Rathkolb B, Wolf E, Hrabé de Angelis M, Roshandel D, Naessens J (2009): Mechanisms controlling anaemia in Trypanosoma congolense infected mice. PLoS One 4(4): e5170

Rubio-Aliaga I, Przemeck GKH, Fuchs H, Gailus-Durner V, Adler T, Hans W, Horsch M, Rathkolb B, Rozman J, Schrewe A, Wagner S, Hölter SM, Becker L, Klopstock T, Wurst W, Wolf E, Klingenspor M, Ivandic BT, Busch DH, Becker J, Hrabé de Angelis M (2009): Dll1 haploinsufficiency in adult mice leads to a complex phenotype affecting metabolic and immunological processes. PLos One 4, e6054

Abe K, Wechs S, Kalaydjiev S, Franz TJ, Busch DH, Fuchs H, Soewarto D, Behrendt H, Wagner S, Jakob T, Hrabé de Angelis M (2008): Novel lymphocyte-independent mechanisms to initiate inflammatory arthritis via bone marrow-derived cells of Ali18 mutant mice. Rheumatology 47, 292-300

Aigner B, Rathkolb B, Herach N, Hrabé de Angelis M, Wanke R, Wolf E (2008): Diabetes models by screening for hyperglycemia in phenotype-driven ENU mouse mutagenesis projects. Am J Physiol Endocrinol Metab 294, E232-E240

Bender A, Beckers J, Schneider I, Hölter SM, Haack T, Ruthsatz T, Vogt-Weisenhorn DM, Becker L, Genius J, Rujescu D, Irmler M, Mijalski T, Mader M., Quintanilla-Martinez ., Fuchs ., Gailus-Durner V, Hrabé de Angelis M, Wurst W, Schmidt J, Klopstock T (2008): Creatine improves health and survival of mice. Neurobiol Aging 29, 1404-1411

Fuchs H, Lisse T, Hans W, Abe K, Thiele F, Gailus-Durner V, Hrabé de Angelis M (2008): Phenotypic characterization of mouse models for bone-related diseases in the German Mouse Clinic. J Musculoskelet Neuronal Interact. 8, 13-14

Ganguly K, Favor J, Neuhäuser-Klaus A, Sandulache R, Puk O, Beckers J, Horsch M, Schädler S, Vogt-Weisenhorn D, Wurst W, Graw . (2008): Novel allele of Crybb2 in the mouse and its expression in the brain. Invest Ophth Vis Sci 49, 1533-1541

Hölter SM, Dalke C, Kallnik M, Becker L, Horsch M, Schrewe A, Favor J, Klopstock T, Beckers J, Ivandic B, Gailus-Durner V, Fuchs H, Hrabé de Angelis M, Graw J, Wurst W (2008): Sighted C3H mice – a tool for analysing the influence of vision on mouse behaviour? Frontiers in Bioscience 13, 5810-5823

Horsch M, Schädler S, Gailus-Durner V, Fuchs H, Meyer H, Hrabé de Angelis M, Beckers J (2008): Systematic gene expression profiling of mouse model series reveals co-expressed genes. Proteomics 8, 1248-1256

Lisse TS, Thiele F, Fuchs H, Hans W, Przemeck GKH., Abe K, Rathkolb B, Quintanilla-Martinez L, Hoelzlwimmer G, Helfrich M, Wolf E, Ralston SH, Hrabé de Angelis M (2008): ER-stress mediated apoptosis in a new mouse model of osteogenesis imperfecta. Neurobiol Aging 29, 1404-1411

Maier H, Lengger C, Simic B, Fuchs H, Gailus-Durner V, Hrabé de Angelis M (2008): MausDB: an open source application for phenotype data and mouse colony management in large-scale mouse phenotyping projects. BMC Bioinformatics 9, 169

Puk O, Dalke C, Hrabé de Angelis M, Graw J (2008): Variation of the response to the optokinetic drum among various strains of mice. Front Biosci. 13, 6269-6275

Puk O, Löster J, Dalke C, Soewarto D, Fuchs H, Budde B, Nürnberg P, Wolf E, Hrabé de Angelis M, Graw J (2008): Mutation in a Novel Connexin-like Gene (Gjf1) in the Mouse Affects Early Lens Development and Causes a Variable Small-Eye Phenotype. Investigative Ophthalmology and Visual Science 49, 1525-1532

Aigner B, Rathkolb B, Herbach N, Kemter E, Schessl C, Klaften M, Klempt M, Hrabé de Angelis M, Wanke R, Wolf E (2007): Screening for increased plasma urea levels in a large-scale ENU mouse mutagenesis project reveals kidney disease models. Am J Physiol Renal Physiol 292, F1560-F1567

Aigner B, Rathkolb B, Mohr M, Klempt M, Hrabé de Angelis M, Wolf E (2007): Generation of ENU-Induced Mouse Mutants with Hypocholesterolemia: Novel Tools for Dissecting Plasma Lipoprotein Homeostasis. Lipids 42, 731-737

Hancock JM, Adams NC, Aidinis V, Blake A, Blake JA, Bogue M, Brown SDM, Chesler E, Davidson D, Duran C, Eppig JT, Gailus-Durner V, Gates H, Gkoutos GV, Greenaway S, Hrabé de Angelis M, Kollias G, Leblanc S, Lee K, Lengger C, Maier H, Mallon A-M, Masuya H, Melvin DG, Müller W, Parkinson H, Proctor G, Reuveni E, Schofield P, Shukla A, Smith C, Toyoda T, Vasseur L, Wakana S, Walling A, White J, Wood J, Zouberakis M (2007): Integration of mouse phenome data resources: The Mouse Phenotype Database Integration Consortium. Mammalian Genome 18, 157-163

Herbach N, Rathkolb B, Kemter E, Pichl L, Klaften M, Hrabé de Angelis M, Halban PA, Wolf E, Aigner B, Wanke R (2007): Dominant negative effects of a novel mutated Ins2 allele causes early onset diabetes mellitus and severe beta cell loss in Munich Ins2C95S mutant mice. Diabetes 56, 1268-1276

Kallnik M, Elvert R, Ehrhardt N, Kissling D, Mahabir E, Welzl G, Faus-Kessler T, Hrabé de Angelis M, Wurst W, Schmidt J, Hölter SM (2007): Impact of IVC housing on emotionality and fear learning in male C3HeB/FeJ and C57BL/6J mice. Mamm Genome 18, 173-186

Magnol L, Chevallier M-C, Nalesso V, Retif S, Fuchs H, Klempt M, Pereira P, Riottot M, Andrzejewski S, Doan B-T, Panthier J-J, Puech A, Beloeil J-C, Hrabé de Angelis M, Hérault Y (2007): KIT is required for hepatic function during mouse post-natal development. BMC Develop Biol 7, doi:10.1186/1471-213X-7-81

Meyer CW, Elvert R, Scherag A, Ehrhardt N, Gailus-Durner V, Fuchs H, Schäfer H, Hrabé de Angelis M, Heldmaier G, Klingenspor M (2007) Power matters in closing the phenotyping gap. Naturwissenschaften 94, 401-406

Prehn C, Ströhle F, Haller F, Keller B, Hrabé de Angelis M, Adamski J, Mindnich, R. (2007): A Comparison Of Methods For Assays Of Steroidogenic Enzymes: New GC/MS Versus HPLC And TLC. Purdue University Press, West Lafayette, Indiana, USA

Rubio-Aliaga I, Soewarto D, Wagner S, Klaften M, Fuchs H, Kalaydjiev S, Busch DH, Klempt M, Rathkolb B, Wolf E, Abe K, Zeiser S, Przemeck GKH, Beckers J, Hrabé de Angelis M (2007): A Genetic Screen for Modifiers of the Delta1-Dependent Notch Signaling Function in the Mouse. Genetics 175, 1-13

Seedorf H, Klaften M, Eke F, Fuchs H, Seedorf U, Hrabé de Angelis M (2007): A Mutation in the Enamelin Gene in a Mouse Model. J Dent Res 86, 764-768

Vauti F, Goller T, Beine R, Becker L, Klopstock T, Hölter SM, Wurst W, Fuchs H, Gailus-Durner V, Hrabé de Angelis M, Arnold H-H (2007): The mouse Trm1-like gene is expressed in neural tissues and plays a role in motor coordination and exploratory behaviour. Gene 389, 174-185

Abe K, Fuchs H, Lisse T, Hans W, Hrabé de Angelis M (2006): New ENU-induced semidominant mutation, ALI18, causes inflammatory arthritis, dermatitis, and osteoporosis in the mouse. Mamm Genome 17, 915-926

del Barco Barrantes I, Montero-Pedrazuela A, Gudano-Ferraz A, Obregon M-J, Martinez de Mena R, Gailus-Durner V, Fuchs H, Franz TJ, Kalaydjiev S, Klempt M, Hölter S, Rathkolb B, Reinhard C, Morreale de Escobar G, Bernal J, Busch DH, Wurst W, Wolf E, Schulz H, Shtrom S, Greiner E, Hrabé de Angelis M, Westphal H, Niehrs C (2006): Generation and Characterization of Dickkopf3 Mutant Mice. Mol Cell Biol 26, 2317-2326

Brielmeier M, Mahabir E, Needham JR, Lengger C, Wilhelm P, and Schmidt J (2006): Microbiological monitoring of laboratory mice and biocontainment in individually ventilated cages: a field study. Laboratory Animals 40, 247–260

Klempt M, Rathkolb B, Fuchs E, Hrabé de Angelis M, Wolf E, Aigner B (2006): Genotype-specific environmental impact on the variance of blood values in inbred and F1 hybrid mice. Mamm Genome 17, 93-102

McGowan KA, Aradadhya S, Fuchs H, Hrabé de Angelis M, Barsh GS (2006): A Mouse Keratin1 Mutation Causes Dark Skin and Epidermolytic Hyperkeratosis. J Invest Dermatol 126, 1013-1016

Puk O, Dalke C, Favor J, Hrabé de Angelis M, Graw J (2006): Variations of eye size parameters among different strains of mice. Mamm Genome 17, 851-857

Schneider I, Tirsch WS, Faus-Keßler T, Becker L, Kling E, Austin Bussi R-L, Bender A, Feddersen B, Tritschler J, Fuchs H, Gailus-Durner V, Englmeier K-H, Hrabé de Angelis M, Klopstock T (2006): Systematic, standardized and comprehensive neurological phenotyping of inbred mice strains in the German Mouse Clinic. J Neurosci Meth 157, 82-90

Brown SDM, Chambon P, Hrabé de Angelis M, (Eumorphia Consortium) (2005): EMPReSS: standarized phenotype screens for functional annotation of the mouse genome. Nature Genetics 37, 1155

Gailus-Durner V, Fuchs H, Becker L, Bolle I, Bielmeier M, Calzada-Wack J, Elvert R, Erhardt N, Dalke C, Franz TJ, Grundner-Culemann E, Hammelbacher S, Hölter S, Hölzlwimmer G, Horsch M, Javaheri A, Kalaydjiev S, Klempt M, Kling E, Kunder S, Lengger C, Lisse T, Mijalski T, Naton B, Pedersen V, Prehn C, Przemeck G, Racz I, Reinhard C, Reitmeir P, Schneider I, Schrewe A, Steinkamp R, Zybill C, Adamski J, Beckers J, Behrendt H, Favor J, Graw J, Heldmaier G, Höfler H, Ivandic B, Katus H, Kirchhof P, Klingenspor M, Klopstock T, Lengeling A, Müller W, Ohl F, Ollert M, Quintanilla-Martinez L, Schmidt J, Schulz H, Wolf E, Wurst W, Zimmer A, Busch DH, and Hrabé de Angelis M (2005): Introducing the German Mouse Clinic: Open access platform for standardized phenotyping. Nat Methods 2, 403-404

Gailus-Durner V, Adamski J, Beckers J, Behrendt H, Busch D, Engelmann B, Floss T, Fuchs H, Graw J, Hansen G, Heldmaier G, Himmelbauer H, Höfler H, Hölter S, Ivandic B, Jakob H, Katus H, Klingenspor M, Laufs J, Lengeling A, Lengger C, Müller W, Nehls M, Ollert M, Quintanilla-Fend L, Ruiz P, Schulz H, von Melchner H, Wolf E, Wurst W, Zeretzke S, Zimmer A, Hrabé de Angelis M (2005): Mäuse als Modelle für erbliche Erkrankungen des Menschen. GENOMXPRESS 2, 7-10

Pasche B, Kalaydjiev S, Franz T, Kremmer E, Gailus-Durner V, Fuchs H, Hrabé de Angelis M, Lengeling A, Busch DH (2005): Sex-Dependent Susceptibilty to Listeria monocytogenes Infection Is Mediated by Differential Interleukin-10 Production. Infect Immun 73, 5952-5960

Reinhard C, Meyer B, Fuchs H, Stoeger T, Eder G, Rüschendorf F, Heyder J, Nürnberg P, Hrabé de Angelis M, Schulz H (2005): Genomewide linkage analysis identifies novel genetic loci for lung function in mice. Am J Resp Crit Care 171, 880-888

Yu P, Constien R, Dear N, Katan M, Hanke P, Bunney TD, Kunder S, Quintanilla-Martinez L, Huffstadt U, Schröder A, Peters T, Fuchs H, Hrabé de Angelis M, Nehls M, Grosse J, Wabnitz P, Meyer TPH, Yasuda K, Schneider-Fresenius C, Jagla W, Russ A, Popp A, Laufs J, Schmittwolf C, Wagner H, Pfeffer K, Mudde GC (2005): Autoimmunity and inflammation due to a gain-of-function mutation in phospholipase C2 that specifically increase external Ca2+ entry. Immunity 22, 451-465

Auwerx J, Avner P, Baldock R, Ballabio A, Balling R, Barbacid M, Berns A, Bradley A, Brown S, Carmeliet P, Chambon P, Cox R, Davidson D, Davies K, Duboule D, Forejt J, Granucci F, Hastie N, Hrabé de Angelis M, Jackson J, Kioussis D, Kollias G, Lathrop M, Lendahl U, Malumbres M, von Melchner H, Müller W, Partanen J, Ricciardi-Castagnoli P, Rigby P, Rosen B, Rosenthal N, Skarnes B, Stewart AF, Thornton J, Tocchini-Valentini G, Wagner E, Wahli W, Wurst W (2004): The European dimension for the mouse genome mutagenesis programm. Nature Genetics 36, 925-927

Dalke C, Löster J, Fuchs H, Gailus-Durner V, Soewarto D, Favor J, Neuhäuser-Klaus A, Pretsch W, Gekeler F, Shinoda K, Zrenner E, Meitinger T, Hrabé de Angelis M, Graw J (2004): Electroretinography as a Screening Methods for Mutations Causing Retinal Dysfunction in Mice. Invest Ophtalmol Vis Sci 45, 601-609

Ivandic B, Kirchhof P, Fuchs H, Gailus-Durner V, Katus H, Hrabé de Angelis M (2004): The German Mouse clinic - Establishment of a new cardiovascular primary screen. Perfusion 9, 373

Meyer CWE, Korthaus D, Jagla W, Cornali E, Grosse J, Fuchs H, Klingenspor M, Roemheld S, Tschöp M, Heldmaier G, Hrabé de Angelis M, Nehls M (2004): A Novel Missense Mutation in the Mouse Growth Hormone Gene Causes Semidominant Dwarfism, Hyperghrelinemia and Obesity. Endocrinology 14, 2531-2541

Mohr M, Klempt M, Rathkolb B, Hrabé de Angelis M, Wolf E, Aigner B (2004): Hypercholesterolemia in ENU-induced mouse mutants. J Lipid Res 45, 2132-2137

Hafezparast M, Klocke R, Ruhrberg C, Marquardt A, Ahmad-Annuar A, Bowen S, Lalli G, Witherden AS, Hummerich H, Nicholson S, Morgan PJ, Oozageer R, Priestly JV, Averill S, King VR, Ball S, Peters J, Toda T, Yamamoto A, Hiraoka Y, Augustin M, Korthaus D, Wattler S, Wabnitz P, Dickneite C, Lampel S, Boehme F, Peraus G, Popp A, Rudelius M, Schlegel J, Fuchs H, Hrabé de Angelis M, Shciavo G, Shima DT, Russ AP, Stumm G, Martin JE, Fisher EMC (2003): Mutations in Dynein link motor neuron degeneration to defects in retrograde transport. Science 300, 808-812

Schulz H, Reinhard C, Eder G, Fuchs H, Meyer B, Rüschendorf F, Hrabé de Angelis M, Nürnberg P, Heyder J (2003): Studies on the inheritance of lung function in a mouse model. Am J Respir Crit Care Med 167, A833

Schulz H, Reinhard C, Eder G, Ziesenis A, Fuchs H, Meyer B, Rüschendorf F, Hrabé de Angelis M, Nürnberg P, Heyder J (2003): Genetic influences respiratory lung function. Eur J Physiol 445, 91

Schulz H, Reinhard C, Eder Ziesenis A, Fuchs H, Hrabé de Angelis M, Nürnberg, P, Heyder J (2003): Variabilität der Lungenfunktion bei Maus-Inzuchtstämmen. Atemw.-Lungenkrkh 29, 331-333

Hrabé de Angelis M, Chambon P, Brown S (eds) (2006): Standards of Mouse Model Phenotyping. John Wiley & Sons Ltd.

Hrabé de Angelis M, Adler A, Beckers J, Soewarto D, Wagner S, Gailus-Durner V, Imai K (2004): ENU mutagenesis. In: The Laboratory Mouse. Hedrich HH, Bullock, G.(eds.), Academic Press, Chapter 4, 47-85

Reinhard C, Eder G, Fuchs H, Ziesenis A, Meyer B, Rueschendorf F, Hrabé de Angelis M, Heyder J, Schulz H (2004): Differences in lung function among mouse inbred strains are genetically determined In: INIS Monographs, Effects of air contaminants on the respiratory tract - Interpretations from molecular to meta analysis. 9. International Inhalation Symposium, Heinrich, U., Stuttgart; Fraunhofer IRB Verlag, 435-444