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GMC - German Mouse Clinic


German Mouse Clinic

GMC - German Mouse Clinic


German Mouse Clinic


Identification of genetic elements in metabolism by high...

Scientists have identified a network of genes that could play an important role in the development of metabolic diseases such as diabetes. The German Mouse Clinic, collaboration partners within the Helmholtz Center Munich and the International Mouse Phenotyping Consortium (IMPC) led the work that...


Female mice lacking Pald1 exhibit endothelial cell apoptosis and...

Paladin or Pald1 is a phosphatase-domain containing protein and was identified in two independent screens for novel regulators of angiogenesis and vascular function. In a collaboration with colleagues in Sweden, the German Mouse Clinic characterized the new Pald1−/− mouse model performing...


IMPC uncovered new genes relevant for hearing

The International Mouse Phenotyping Consortium (IMPC) including the German Mouse Clinic, Helmholtz Zentrum München, succeeded in shedding light on more than 50 new hearing genes. The study was recently published in Nature Communications.The developmental and physiological complexity of the...


Is CatWalk sufficient for locomotor analysis?

Efficient phenotyping is essential for the identification of relevant changes and phenotypes and for the reproducibility of scientific experiments. A number of automated tests have been developed to speed up data acquisition, to make the results more objective and replicable and to reduce the...


Paternal diet influences cognitive functions in offspring

While it is recognized that maternal departures from the optimum of dietary methyl donor intake, such as folic acid, methionine or vitamine B12, can increase the risk for mental health issues and neurological disorders in offspring, it has not been explored whether paternal dietary methyl donor...

Phenotype your mouse model


  1. Systemic, comprehensive phenotyping in 14 different disease areas
  2. Customized primary phenotypic screening in specific areas of interest (e.g. behavior, neurology and neuropathology)


  1. Hypothesis-driven phenotypic analysis using environmental challenges
  2. Combining environmental challenges


  1. Systemic analysis of compounds and drugs

View results of mutant lines

View the results of mutant mouse lines in the GMC phenomap.

IMPC - Intl Mouse Phenotyping Consortium

View the status of IMPC lines and their phenotyping results.

How primary mouse phenotyping leads to novel insights for human health

Mouse phenotyping helps to better understand human diseases. Read more how systemic primary screening of mouse mutants uncovers unexpected new gene functions.

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The GMC Consortium

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