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GMC - German Mouse Clinic

GMC

German Mouse Clinic

GMC - German Mouse Clinic

GMC

German Mouse Clinic

16.01.2024

Single-cell sequencing based catalog of genetic developmental disorders

Genetic malformations often occur during early pregnancy and unraveling the genetic basis for the resulting disorder is challenging. Current...

22.09.2023

DHX9 - New candidate gene for neurodevelopmental disorders and Charcot-Marie-Tooth disease

A team of scientists at the Baylor College of Medicine, the Chinese University of Hong Kong, the German Mouse Clinic and collaborating institutions...

01.08.2023

AOX delays the onset of symptoms in Uqcrh KO mouse, a model of complex III disease.

Mitochondrial diseases are rare and complex genetic disorders that impair energy production, often leading to deficiencies in the oxidative chain....

13.06.2023

SERF2 - a new player contributing to amyloid pathology in the brain?

Currently more than 55 million people have dementia worldwide and every year there are nearly 10 million new cases. Dementia is currently the seventh...

19.04.2023

Knockout mice are an important tool for human monogenic heart disease studies

Monogenic diseases are individually rare but collectively quite common, posing a huge burden on families and society. Monogenic cardio vascular...

Phenotype your mouse model

GMC I: 

  1. Systemic, comprehensive phenotyping in 14 different disease areas
  2. Customized primary phenotypic screening in specific areas of interest (e.g. behavior, neurology and neuropathology)

GMC II: 

  1. Hypothesis-driven phenotypic analysis using environmental challenges
  2. Combining environmental challenges

GMCIII:

  1. Systemic analysis of compounds and drugs

View results of mutant lines

View the results of mutant mouse lines in the GMC phenomap.

How primary mouse phenotyping leads to novel insights for human health

Mouse phenotyping helps to better understand human diseases. Read more how systemic primary screening of mouse mutants uncovers unexpected new gene functions.

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