News

MTO1 - mouse model mirrows human phenotype

13.02.2015 | Mutations in nuclear-encoded mitochondrial genes or mitochondrial DNA (mtDNA) lead to a plethora of...

AOC3 – modelling allergic inflammation

10.02.2015 | The immunopathogenesis of asthma involves complex cross-talk between airway epithelial cells,...

Slc12a1I299F – mouse mutation mimicks human phenotype (and more)

06.02.2015 | Type I Bartter syndrome is a rare hereditary recessive human kidney disease with a severe urinary...

Phenotype your mouse model

GMC I: 

  1. Systemic, comprehensive phenotyping in 14 different disease areas
  2. Customized primary phenotypic screening in specific areas of interest (e.g. behavior, neurology and neuropathology)

GMC II: 

  1. Hypothesis-driven phenotypic analysis using environmental challenges
  2. Combining environmental challenges

GMCIII:

  1. Systemic analysis of compounds and drugs

TÜV Süd certified Quality Management

Collaborators in primary screening per country

Director

Prof. Dr. Martin Hrabě de Angelis

View results of mutant lines

View the results of mutant mouse lines in the GMC phenomap

IMPC - Intl Mouse Phenotyping Consortium

How primary mouse phenotyping leads to novel insights for human health

Mouse phenotyping helps to better understand human diseases. Here we present an example how systemic primary screening of mouse mutants uncovers unexpected new gene functions.  Read more...

The GMC Consortium:

We are partners in: