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GMC - German Mouse Clinic


German Mouse Clinic

GMC - German Mouse Clinic


German Mouse Clinic


Knockout mice are an important tool for human monogenic heart disease studies

Monogenic diseases are individually rare but collectively quite common, posing a huge burden on families and society. Monogenic cardio vascular...


Longevity treatments do not slow aging

Three approaches with a reputation for slowing aging processes have proven largely ineffective. For their study, researchers developed a new method to...


Novel neurodevelopment syndrome caused by RABGAP1 deficiency

There are no known Mendelian diseases caused by variants in RABGAP1 yet. Clinicians and Scientists either caring for patients with rare homozygous...


New mouse model for interventional obesity research

Suitable animal models are essential for translational research, especially in the case of complex, multifactorial conditions, such as obesity. In...


New candidate genes for congenital heart defects

A heart defect is the most common congenital malformation, every 100th child is born with it. These genetic disorders include subsets of inherited...

Phenotype your mouse model


  1. Systemic, comprehensive phenotyping in 14 different disease areas
  2. Customized primary phenotypic screening in specific areas of interest (e.g. behavior, neurology and neuropathology)


  1. Hypothesis-driven phenotypic analysis using environmental challenges
  2. Combining environmental challenges


  1. Systemic analysis of compounds and drugs

View results of mutant lines

View the results of mutant mouse lines in the GMC phenomap.

How primary mouse phenotyping leads to novel insights for human health

Mouse phenotyping helps to better understand human diseases. Read more how systemic primary screening of mouse mutants uncovers unexpected new gene functions.

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