Logo Helmholtz Zentrum München
GMC - German Mouse Clinic


German Mouse Clinic

GMC - German Mouse Clinic


German Mouse Clinic


Study unravel intergenerational effects of advanced paternal age...

Advanced age is a risk factor for many age related disorders, and it may enhance susceptibility for disease in the next generation. The recent joint publication of the DZNE Bonn and the German Mouse Clinic reports a reduced life span and an exacerbated development of aging traits in old father...


Identification of genetic elements in metabolism by high...

Scientists have identified a network of genes that could play an important role in the development of metabolic diseases such as diabetes. The German Mouse Clinic, collaboration partners within the Helmholtz Center Munich and the International Mouse Phenotyping Consortium (IMPC) led the work that...


Female mice lacking Pald1 exhibit endothelial cell apoptosis and...

Paladin or Pald1 is a phosphatase-domain containing protein and was identified in two independent screens for novel regulators of angiogenesis and vascular function. In a collaboration with colleagues in Sweden, the German Mouse Clinic characterized the new Pald1−/− mouse model performing...


IMPC uncovered new genes relevant for hearing

The International Mouse Phenotyping Consortium (IMPC) including the German Mouse Clinic, Helmholtz Zentrum München, succeeded in shedding light on more than 50 new hearing genes. The study was recently published in Nature Communications.The developmental and physiological complexity of the...


Is CatWalk sufficient for locomotor analysis?

Efficient phenotyping is essential for the identification of relevant changes and phenotypes and for the reproducibility of scientific experiments. A number of automated tests have been developed to speed up data acquisition, to make the results more objective and replicable and to reduce the...

Phenotype your mouse model


  1. Systemic, comprehensive phenotyping in 14 different disease areas
  2. Customized primary phenotypic screening in specific areas of interest (e.g. behavior, neurology and neuropathology)


  1. Hypothesis-driven phenotypic analysis using environmental challenges
  2. Combining environmental challenges


  1. Systemic analysis of compounds and drugs

View results of mutant lines

View the results of mutant mouse lines in the GMC phenomap.

IMPC - Intl Mouse Phenotyping Consortium

View the status of IMPC lines and their phenotyping results.

How primary mouse phenotyping leads to novel insights for human health

Mouse phenotyping helps to better understand human diseases. Read more how systemic primary screening of mouse mutants uncovers unexpected new gene functions.

TÜV Süd certified Quality Management

The GMC Consortium

We are partners in