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GMC - German Mouse Clinic

GMC

German Mouse Clinic

GMC - German Mouse Clinic

GMC

German Mouse Clinic

08.06.2021

Whole‑body Wdr45 knock‑out mouse: Systemic view on the rare neurological disorder BPAN

In this recent study, scientists from the Helmholtz Center Munich generated and extensively characterized a new mouse model for the rare neurological...

28.04.2021

Central role of Creld1 in mammalian heart development and function

Scientists from the University of Bonn in collaboration with colleagues from Radboud University, Nijmegen and the German Mouse Clinic showed, that Cre...

11.01.2021

Novel Genes That Influence Bone Mineral Density

Researchers from Helmholtz Zentrum München, together with the International Mouse Phenotyping Consortium (IMPC), have uncovered a large number of...

24.11.2020

Increased estrogen to androgen ratio in mice feminize the male immune system

In a common effort, scientists of the German Mouse Clinic and Turku University examined the immune system of genetically modified mice that develop...

16.11.2020

New methyltransferase METTL6 and its role in cancer

Methylations are among the most prevalent RNA modifications and multiple METTL proteins have been implicated in different types of cancers. In a...

Phenotype your mouse model

GMC I: 

  1. Systemic, comprehensive phenotyping in 14 different disease areas
  2. Customized primary phenotypic screening in specific areas of interest (e.g. behavior, neurology and neuropathology)

GMC II: 

  1. Hypothesis-driven phenotypic analysis using environmental challenges
  2. Combining environmental challenges

GMCIII:

  1. Systemic analysis of compounds and drugs

View results of mutant lines

View the results of mutant mouse lines in the GMC phenomap.

How primary mouse phenotyping leads to novel insights for human health

Mouse phenotyping helps to better understand human diseases. Read more how systemic primary screening of mouse mutants uncovers unexpected new gene functions.

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The GMC Consortium

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