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GMC - German Mouse Clinic


German Mouse Clinic

GMC - German Mouse Clinic


German Mouse Clinic


Whole‑body Wdr45 knock‑out mouse: Systemic view on the rare neurological disorder BPAN

In this recent study, scientists from the Helmholtz Center Munich generated and extensively characterized a new mouse model for the rare neurological...


Central role of Creld1 in mammalian heart development and function

Scientists from the University of Bonn in collaboration with colleagues from Radboud University, Nijmegen and the German Mouse Clinic showed, that Cre...


Novel Genes That Influence Bone Mineral Density

Researchers from Helmholtz Zentrum München, together with the International Mouse Phenotyping Consortium (IMPC), have uncovered a large number of...


Increased estrogen to androgen ratio in mice feminize the male immune system

In a common effort, scientists of the German Mouse Clinic and Turku University examined the immune system of genetically modified mice that develop...


New methyltransferase METTL6 and its role in cancer

Methylations are among the most prevalent RNA modifications and multiple METTL proteins have been implicated in different types of cancers. In a...

Phenotype your mouse model


  1. Systemic, comprehensive phenotyping in 14 different disease areas
  2. Customized primary phenotypic screening in specific areas of interest (e.g. behavior, neurology and neuropathology)


  1. Hypothesis-driven phenotypic analysis using environmental challenges
  2. Combining environmental challenges


  1. Systemic analysis of compounds and drugs

View results of mutant lines

View the results of mutant mouse lines in the GMC phenomap.

How primary mouse phenotyping leads to novel insights for human health

Mouse phenotyping helps to better understand human diseases. Read more how systemic primary screening of mouse mutants uncovers unexpected new gene functions.

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