GMC

German Mouse Clinic

GMC

German Mouse Clinic

News

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28.05.2024

Rare inborn disorders of lysine metabolism – CHARLIE meeting 2024 hosted by the German Mouse Clinic

On April 29^th and 30^th, the second F2F CHARLIE Consortium meeting took place at Helmholtz Munich, organized by the German Mouse Clinic (GMC) as…

08.05.2024

New insights in transcription factor FOXD2 dysfunction and kidney diseases

Congenital anomalies of the kidney and the urinary tract (CAKUT) are the predominant cause for chronic kidney disease below age 30 years and the main…

16.01.2024

Single-cell sequencing based catalog of genetic developmental disorders

Genetic malformations often occur during early pregnancy and unraveling the genetic basis for the resulting disorder is challenging. Current…

22.09.2023

DHX9 - New candidate gene for neurodevelopmental disorders and Charcot-Marie-Tooth disease

A team of scientists at the Baylor College of Medicine, the Chinese University of Hong Kong, the German Mouse Clinic and collaborating institutions…

01.08.2023

AOX delays the onset of symptoms in Uqcrh KO mouse, a model of complex III disease.

Mitochondrial diseases are rare and complex genetic disorders that impair energy production, often leading to deficiencies in the oxidative chain.…

Phenotype your mouse model

GMC I:

Systemic, comprehensive phenotyping in 14 different disease areas
Customized primary phenotypic screening in specific areas of interest (e.g. behavior, neurology and neuropathology)

GMC II:

Hypothesis-driven phenotypic analysis using environmental challenges
Combining environmental challenges

GMCIII:

Systemic analysis of compounds and drugs

View results of mutant lines

View the results of mutant mouse lines in the GMC phenomap.

How primary mouse phenotyping leads to novel insights for human health

Mouse phenotyping helps to better understand human diseases. Read more how systemic primary screening of mouse mutants uncovers unexpected new gene functions.