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GMC - German Mouse Clinic


German Mouse Clinic

GMC - German Mouse Clinic


German Mouse Clinic


Single-cell sequencing based catalog of genetic developmental disorders

Genetic malformations often occur during early pregnancy and unraveling the genetic basis for the resulting disorder is challenging. Current...


DHX9 - New candidate gene for neurodevelopmental disorders and Charcot-Marie-Tooth disease

A team of scientists at the Baylor College of Medicine, the Chinese University of Hong Kong, the German Mouse Clinic and collaborating institutions...


AOX delays the onset of symptoms in Uqcrh KO mouse, a model of complex III disease.

Mitochondrial diseases are rare and complex genetic disorders that impair energy production, often leading to deficiencies in the oxidative chain....


SERF2 - a new player contributing to amyloid pathology in the brain?

Currently more than 55 million people have dementia worldwide and every year there are nearly 10 million new cases. Dementia is currently the seventh...


Knockout mice are an important tool for human monogenic heart disease studies

Monogenic diseases are individually rare but collectively quite common, posing a huge burden on families and society. Monogenic cardio vascular...

Phenotype your mouse model


  1. Systemic, comprehensive phenotyping in 14 different disease areas
  2. Customized primary phenotypic screening in specific areas of interest (e.g. behavior, neurology and neuropathology)


  1. Hypothesis-driven phenotypic analysis using environmental challenges
  2. Combining environmental challenges


  1. Systemic analysis of compounds and drugs

View results of mutant lines

View the results of mutant mouse lines in the GMC phenomap.

How primary mouse phenotyping leads to novel insights for human health

Mouse phenotyping helps to better understand human diseases. Read more how systemic primary screening of mouse mutants uncovers unexpected new gene functions.

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