Monogenic diseases are individually rare but collectively quite common, posing a huge burden on families and society. Monogenic cardio vascular...

Three approaches with a reputation for slowing aging processes have proven largely ineffective. For their study, researchers developed a new method to...

There are no known Mendelian diseases caused by variants in RABGAP1 yet. Clinicians and Scientists either caring for patients with rare homozygous...

Suitable animal models are essential for translational research, especially in the case of complex, multifactorial conditions, such as obesity. In...

A heart defect is the most common congenital malformation, every 100th child is born with it. These genetic disorders include subsets of inherited...