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GMC - German Mouse Clinic

GMC

German Mouse Clinic

GMC - German Mouse Clinic

GMC

German Mouse Clinic

27.09.2022

Novel neurodevelopment syndrome caused by RABGAP1 deficiency

There are no known Mendelian diseases caused by variants in RABGAP1 yet. Clinicians and Scientists either caring for patients with rare homozygous...

12.05.2022

New mouse model for interventional obesity research

Suitable animal models are essential for translational research, especially in the case of complex, multifactorial conditions, such as obesity. In...

02.03.2022

New candidate genes for congenital heart defects

A heart defect is the most common congenital malformation, every 100th child is born with it. These genetic disorders include subsets of inherited...

09.12.2021

Uqcrh – a new player in mitochondrial complex III disorders

Medicine sheds light on the UQCRH gene and mitochondrial complex III diseases. An international team led by researchers and clinicians from Helmholtz...

02.11.2021

Insights into the genesis of migraine

In this current study scientists teamed up to unraveled the mechanistic cascade underlying cortical spreading depression (CSD) and migraine...

Phenotype your mouse model

GMC I: 

  1. Systemic, comprehensive phenotyping in 14 different disease areas
  2. Customized primary phenotypic screening in specific areas of interest (e.g. behavior, neurology and neuropathology)

GMC II: 

  1. Hypothesis-driven phenotypic analysis using environmental challenges
  2. Combining environmental challenges

GMCIII:

  1. Systemic analysis of compounds and drugs

View results of mutant lines

View the results of mutant mouse lines in the GMC phenomap.

How primary mouse phenotyping leads to novel insights for human health

Mouse phenotyping helps to better understand human diseases. Read more how systemic primary screening of mouse mutants uncovers unexpected new gene functions.

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