Eye screen
The eye screen provides a comprehensive evaluation of the visual systems of incoming mice, recognizing the eye as a complex sensory organ. It combines primary and secondary screening methods to assess both structural and functional aspects of vision. Utilizing advanced imaging technologies, functional tests, and histological analysis, this approach offers a thorough assessment of ocular health and visual capabilities. By integrating these methods, the eye screen delivers precise, reliable insights, advancing visual research with exceptional accuracy.
Primary Screen
The primary screen focuses on anatomical and functional evaluation of the eye using the following advanced technologies:
- Scheimpflug Imaging: Examines the anterior part of the eye, including the cornea and lens.
- Optical Coherence Tomography (OCT): Investigates the posterior part of the eye, including the fundus and retinal layers.
- Laser Interference Biometry (LIB): Measures the axial length of the eye (distance between the cornea and retina).
- Virtual Vision Test: Assesses visual function through head-tracking responses to a rotating stripe pattern.
Secondary Screen
For in-depth analysis, secondary screening is performed on selected groups (5-15 mice per group, per sex):
- Electroretinography (ERG): Evaluates retinal function through advanced signal measurements.
- Histology: Analyzes mouse eye sections, it provides detailed insights into the cellular and tissue-level organization of the eye.