The GMC offers the examination of mouse mutants using a broad standardised phenotypic check-up. The screens in the German Mouse Clinic are designated to the areas of behaviour, bone and cartilage development, neurology, clinical chemistry, eye development, immunology, allergy, steroid metabolism, energy metabolism, lung function, vision and pain perception, molecular phenotyping, cardiovascular and pathology.

Mouse mutants entering the German Mouse Clinic are first examined in a primary screen, which comprises basic screening procedures in all areas. Interesting outliers uncovered by the primary assays can be subjected to more detailed analysis in a secondary and tertiary screen.